U.S. stocks were higher, with the Dow Jones gaining over 100 points on Monday.

Shares of Sarepta Therapeutics Inc (NASDAQ:SRPT) rose sharply during Monday's session after the company released topline three-year functional results from Part 1-treated patients in the EMBARK (Study SRP-9001-301) Phase 3 study of Elevidys (delandistrogene moxeparvovec-rokl) in ambulatory individuals with Duchenne muscular dystrophy.

Three years after treatment, patients who received Elevidys in Part 1 of EMBARK demonstrated statistically significant, clinically meaningful, and durable efficacy across all key motor function measures, North Star Ambulatory Assessment (NSAA), Time to Rise (TTR), and 10-meter walk/run (10MWR), when compared to a pre-specified propensity-weighted untreated external control group.

Sarepta Therapeutics shares jumped 9.8% to $23.20 on Monday.

Here are some other big stocks recording gains in today’s session.

• Lands’ End Inc (NASDAQ:LE) shares jumped 38.8% to $19.51 after the company announced an agreement to form a new joint venture with WHP Global unlock the value of Lands’ End’s intellectual property.
• Alpha Technology Group Ltd (NASDAQ:ATGL) gained 26.8% to $23.61.
• Rich Sparkle Holdings Ltd (NASDAQ:ANPA) gained 22% to $64.66.
• TRX Gold Corp (NYSE:TRX) gained 18% to $1.34. Shares of precious metals traded higher as investors seek safe-haven assets after President Trump recently announced he would impose a 100% tariff on Canada, and concerns about a partial government shutdown if a deal is not reached by Friday’s deadline.
• Northern Dynasty Minerals Ltd (NYSE:NAK) rose 18% to $2.54. Shares of rare-earth mineral stocks traded higher amid sympathy with USA Rare Earth after the Trump administration acquired a 10% stake in the company.
• GoldMining Inc (NYSE:GLDG) shares jumped 17.4% to $2.22. Shares of precious metals traded higher as investors seek safe-haven assets after President Trump recently announced he would impose a 100% tariff on Canada, and concerns about a partial government shutdown if a deal is not reached by Friday’s deadline.
• Greenwich Lifesciences Inc (NASDAQ:GLSI) shares surged 14.4% to $29.15. The company last week announced the Food and Drug Administration approved the use of its first commercially manufactured GP2 lot for the FLAMINGO-01 Phase III clinical trial.
• USA Rare Earth Inc (NASDAQ:USAR) shares climbed 14.3% to $28.31 after the company announced a non-binding letter of intent with the U.S. government for access to $1.6 billion in funding to accelerate the domestic rare earth value chain.
• Zoom Communications Inc (NASDAQ:ZM) gained 10.5% to $94.83.
• Almonty Industries Inc (NASDAQ:ALM) shares rose 10.2% to $12.24.
• Cloudflare Inc (NYSE:NET) shares climbed 10.2% to $191.11 amid a broader market rally.
• CoreWeave Inc (NASDAQ:CRWV) gained 9.5% to $101.88 after the company announced an expanded collaboration with Nvidia Corporation (NASDAQ:NVDA) to accelerate the buildout of more than 5 gigawatts of AI factories by 2030 to advance AI adoption at global scale.

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