On March 13, 2026, Lyra Therapeutics, Inc. (the "Company") received a letter (the "Letter") from the Nasdaq Hearings Advisor at The Nasdaq Stock Market LLC ("Nasdaq") confirming that the Company has withdrawn its appeal of the delisting determination issued by Nasdaq's Listings Qualifications Staff on February 2, 2026. The Letter further confirms that as a result of the withdrawal of the Company's appeal, trading in the Company's common stock will be suspended at the open of trading on Tuesday, March 17, 2026.

In connection with the suspension of trading, Nasdaq has indicated that it will file a Form 25 Notification of Delisting with the U.S. Securities and Exchange Commission after all internal procedural periods have run.