- ARV-102 reduced endolysosomal and neuroinflammatory biomarkers implicated in Parkinson's disease and progressive supranuclear palsy.
- ARV-102 was well tolerated across all dose levels following 28 days of once-daily dosing.
- Data support further development of ARV-102 in additional neurodegenerative diseases characterized by lysosomal dysfunction, including progressive supranuclear palsy, a rapidly progressing and devastating tauopathy
Arvinas' Data From Phase 1 Trial Of Arv-102, Demonstrates Approximately 50% Or Greater Reduction Of LRRK2 In Cerebrospinal Fluid At All Doses By Day 14 And Maintaining The Reduction Through Day 28 In Parkinson's Disease Patients
ARV-102 reduced endolysosomal and neuroinflammatory biomarkers implicated in Parkinson's disease and progressive supranuclear palsy.ARV-102 was well tolerated across all dose levels following 28 days of once-daily
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