Nexalin Technology, Inc. (NASDAQ:NXL) on Thursday announced another publication of a peer-reviewed study in BMC Psychiatry related to the company's Deep Intracranial Frequency Stimulation (DIFS) technology.

Data Shows Reduction In Self-Injury And Depressive Symptoms

The data reported that Nexalin's DIFS 77.5 Hz high-gamma approach was associated with statistically significant reductions in self-injury behaviors and depressive symptoms in female adolescents with non-suicidal self-injury (NSSI).

The study also reported measurable changes in brain-network activity and connectivity, providing additional neurophysiological evidence supporting Nexalin's non-invasive, high-power DIFS technology.

Evidence Supports Brain Network Changes

The analysis evaluated six female adolescent patients who received 21 days of 77.5 Hz, 15 mA stimulation using Nexalin's device.

The paper found changes in functional connectivity across emotional-control networks, including Default, Limbic, Salience/Ventral Attention, and Control networks.

The findings also showed improvement in anxiety and sleep quality measures.

No significant adverse effects were observed, with only one mild headache reported that resolved quickly.

The authors described the findings as preliminary evidence supporting further investigation in larger randomized controlled trials.

Nexalin Executives Highlight Mechanism And Market Potential

David Owens, Chief Medical Officer of Nexalin, said, "This publication is important because it extends the scientific case for Nexalin's high-gamma DIFS technology into one of the most urgent and difficult-to-treat populations in mental health…We believe these findings further support the underlying mechanism of our 77.5 Hz, 15 mA neurostimulation approach and add to the growing body of peer-reviewed evidence validating Nexalin's platform."

Mark White, CEO of Nexalin, added, "The Nexalin 15 mAmp DIFS technology allows for deeper penetration, which supports higher efficacy and enhanced treatment outcomes in a treatment-resistant population. In a market seeking safer, drug-free alternatives in mental health, each additional peer-reviewed publication helps further validate our technology and broaden its relevance across multiple indications."

In February, Nexalin launched its new AI-designed virtual clinic platform, NeuroCare, in collaboration with the University of California, San Diego.

The launch marked the first step in deploying Nexalin's digital health ecosystem, designed to increase patient access, reduce costs, and provide long-term physician-patient care and monitoring across critical brain-health indications.

NXL Stock Price Activity: Nexalin shares closed at $0.35 on Wednesday, according to Benzinga Pro data.

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