Akari Therapeutics, Plc (NASDAQ:AKTX), an oncology biotechnology company developing antibody drug conjugates (ADCs) with novel RNA splicing modulator payloads, today announced the grant of a major European patent that significantly strengthens its global intellectual property position and underscores the differentiation of its proprietary PH1 ADC payload platform.

The newly granted patent (European Patent No. 3684773B1), titled "Thailanstatin Analogs," provides broad composition-of-matter protection for Akari's proprietary Thailanstatin-based payloads, engineered for use in highly targeted cytotoxic ADC therapies. The claims encompass novel analogs designed to integrate with advanced linker technologies and enable targeting across multiple tumor-associated antigens.