On May 12, 2026, Coya Therapeutics, Inc. (the "Company") entered into a Sales Agreement (the "Sales Agreement") with Leerink Partners LLC, as sales agent ("Leerink Partners"), pursuant to which the Company may offer and sell, from time to time through or to Leerink Partners, shares of the Company's common stock, par value $0.0001 per share ("Common Stock"), for aggregate gross proceeds of up to $30,000,000 (the "Placement Shares"). The offer and sale of the Placement Shares will be made pursuant to a shelf registration statement on Form S-3 (File No. 333-289511) and the related prospectus, as supplemented by a prospectus supplement dated May 12, 2026 (the "Registration Statement") and filed with the Securities and Exchange Commission on such date pursuant to Rule 424(b) under the Securities Act of 1933, as amended (the "Securities Act").