• First Zeta-navigated TMS treatments have begun at HOPE Therapeutics clinics in West Palm Beach and Sarasota, Florida, marking the transition from research deployment to active patient care
  • AI-powered, sub-millimetric image guidance is now being applied in HOPE's outpatient TMS workflows for patients with Major Depressive Disorder and other CNS conditions
  • Milestone advances HOPE's interventional psychiatry platform and aligns with NRx's planned trial of NRX-101 in combination with robotic-enabled TMS in civilian and military treatment facilities (the SPARC-TMS trial).

WILMINGTON, Del., June 25, 2026 (GLOBE NEWSWIRE) -- NRx Pharmaceuticals, Inc. (NASDAQ:NRXP) ("NRx Pharmaceuticals", "NRx" or the "Company"), a clinical-stage biopharmaceutical company, today announced that its subsidiary, HOPE Therapeutics, Inc. ("HOPE"), has treated its first patients using Zeta Surgical's FDA-cleared Zeta TMS Navigation System. HOPE has installed Zeta TMS Navigation Systems at its clinics in West Palm Beach and Sarasota, Florida, with Zeta-navigated patient treatments now underway at both locations.

The first treatments mark HOPE's transition from system deployment to active patient care, bringing AI-powered, sub-millimetric image guidance into routine outpatient TMS workflows for patients with Major Depressive Disorder and other neurological conditions. The Zeta TMS Navigation System uses proprietary RealTrack™ technology to provide real-time, markerless image guidance for TMS procedures, applying artificial intelligence and computer vision to register a patient's MRI or CT imaging to their facial anatomy in under two minutes and to continuously track the position of the TMS coil relative to the planned brain target with sub-millimetric accuracy.