• Six presentations planned, including encore oral presentation of topline X-TOLE2 efficacy and safety results

     
  • New poster will highlight the mechanistic characterization of azetukalner, including its potential additive effects when used with commonly prescribed ASMs



     

VANCOUVER, BC and BOSTON, MA, Aug. 26, 2026 (GLOBE NEWSWIRE) -- Xenon Pharmaceuticals Inc. (NASDAQ:XENE), a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need, today announced multiple data presentations at the upcoming 16th European Epilepsy Congress (EEC), taking place September 5-9, 2026, in Athens, Greece.

Six presentations are planned, including an oral presentation of the topline Phase 3 X-TOLE2 study results for azetukalner in focal onset seizures (FOS), as well as two poster presentations related to long-term seizure reduction, seizure freedom, and safety and tolerability among patients with FOS who have participated in the ongoing X-TOLE Open Label Extension (OLE) study for at least 48 months.

Additionally, a new poster highlighting the mechanistic characterization of azetukalner will also be presented, including KV7 binding, enhanced channel opening, and rational polytherapy potential. This poster will include in vivo data demonstrating the potential additive effects of azetukalner when used in combination with commonly prescribed antiseizure medications (ASMs), reinforcing its opportunity to enhance seizure control through the application of rational polytherapy in clinical practice.