• First and only FDA-approved therapy for the treatment of acquired hypothalamic obesity, a rare disease characterized by accelerated and sustained weight gain caused by hypothalamic injury or dysfunction
  • Indicated to reduce excess body weight and maintain reduction long-term in adults and pediatric patients aged 4 years and older with acquired hypothalamic obesity
  • Approval based on -18.4% placebo-adjusted BMI reduction achieved by setmelanotide in global Phase 3 TRANSCEND trial [N=142]