Achieved 100% ORR and 83.3% CR rate at dose level 2 following a single infusion in patients with relapsed/refractory B-NHL in an ongoing Phase 1 study
Single infusion of LB2501 generated dose-dependent in vivo CAR-T expansion without lymphodepletion
No dose-limiting toxicities, serious adverse events, ICANS, or deaths were reported; infusion-related reactions and CRS were Grade 1–2, and none required glucocorticoids for CRS management
Additional translational data showed rapid vector clearance, polyclonal vector integration, and no evidence of non-specific transduction
Proof-of-concept progress demonstrates leadership in next-generation cell therapies, with results presented in a late-breaking session at EHA 2026
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