Topline Phase 3 Results from C-FORWARD Expected Around Year-End 2026

More Than 880 HCV Treatment-Naïve Patients Enrolled Across 17 Countries Outside North America

C-FORWARD and C-BEYOND Represent the First Global Phase 3 Head-to-Head Trials of Direct-Acting Antivirals for the Treatment of HCV

BOSTON, June 25, 2026 (GLOBE NEWSWIRE) -- Atea Pharmaceuticals, Inc. (NASDAQ:AVIR) (Atea or Company), a late-stage clinical biopharmaceutical company engaged in the discovery and development of oral antiviral therapeutics for serious viral diseases, today announced completion of patient enrollment in C-FORWARD, its Phase 3 clinical trial outside North America, evaluating the regimen of bemnifosbuvir and ruzasvir (BEM/RZR) for the treatment of hepatitis C virus (HCV) infection. The anticipated topline results from C-BEYOND, the Phase 3 trial conducted in the US and Canada, remain on track for mid-year 2026.

C-FORWARD enrolled more than 880 treatment-naïve patients across approximately 120 clinical sites in 17 countries. The trial is evaluating the fixed-dose combination regimen of BEM/RZR against a current standard of care – the fixed-dose combination regimen of sofosbuvir and velpatasvir – in patients with chronic HCV infection. Topline results from C-FORWARD are expected around year-end 2026. Notably, patients enrolled in C-FORWARD have a diverse range of HCV genotypes, including genotypes more commonly observed outside North America, supporting the potential for a broad treatment label.