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Affinity Asset Advisors, LLC
Period ended Jun 30, 2026 · Latest filing Aug 13, 2026
These quarterly holdings are delayed and may not include all assets or short positions.
Values are from the reporting date, not current prices or purchase costs.
The same security may appear in multiple rows.
Source: SEC
Reported portfolio value
Quarter-end reported holdings; not current value or investment performance.
View reported values
- Jun 30, 2026: $2,212,480,490
More quarters will appear as history becomes available.
Top holdings
Top 10 at Jun 30, 2026. Matching entries are combined; security classes and options remain separate. Shares exclude principal amounts; option shares reflect the reported underlying amount.
View top holdings values
- ROIVANT SCIENCES LTD · SHS · G76279101 · shares: $132,712,500
- APOGEE THERAPEUTICS INC · COM · 03770N101 · shares: $131,004,510
- SPYRE THERAPEUTICS INC · COM NEW · 00773J202 · shares: $113,561,517
- XENON PHARMACEUTICALS INC · COM · 98420N105 · shares: $96,274,200
- ERASCA INC · COM · 29479A108 · shares: $96,180,000
- INSMED INC · COM PAR $.01 · 457669307 · shares: $69,303,000
- PRAXIS PRECISION MEDICINES I · COM NEW · 74006W207 · shares: $61,936,150
- ALKERMES PLC · SHS · G01767105 · shares: $58,944,375
- ORUKA THERAPEUTICS INC · COM · 687604108 · shares: $56,150,300
- ANAPTYSBIO INC · COM · 032724106 · shares: $55,762,358
Reported holdings
113 reported entries| Issuer | Class | CUSIP | Type | Shares / principal | Reported value (USD) |
|---|---|---|---|---|---|
| ROIVANT SCIENCES LTD | SHS | G76279101 | — | 3,750,000 shares | $132,712,500 |
| APOGEE THERAPEUTICS INC | COM | 03770N101 | — | 987,000 shares | $131,004,510 |
| SPYRE THERAPEUTICS INC | COM NEW | 00773J202 | — | 1,279,134 shares | $113,561,517 |
| XENON PHARMACEUTICALS INC | COM | 98420N105 | — | 1,595,000 shares | $96,274,200 |
| ERASCA INC | COM | 29479A108 | — | 5,250,000 shares | $96,180,000 |
| INSMED INC | COM PAR $.01 | 457669307 | — | 650,000 shares | $69,303,000 |
| PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 | — | 185,000 shares | $61,936,150 |
| ALKERMES PLC | SHS | G01767105 | — | 1,125,000 shares | $58,944,375 |
| ORUKA THERAPEUTICS INC | COM | 687604108 | — | 590,000 shares | $56,150,300 |
| ANAPTYSBIO INC | COM | 032724106 | — | 826,109 shares | $55,762,358 |
| AVALO THERAPEUTICS INC | COM NEW | 05338F306 | — | 2,900,000 shares | $53,592,000 |
| CYTOKINETICS INC | COM NEW | 23282W605 | — | 550,000 shares | $46,854,500 |
| REVOLUTION MEDICINES INC | COM | 76155X100 | — | 250,000 shares | $46,820,000 |
| ABIVAX SA | SPONSORED ADS | 00370M103 | — | 330,000 shares | $43,975,800 |
| FIRST TRACKS BIOTHERAPEUTICS | ORD SHS | 337185102 | — | 2,032,012 shares | $40,884,081 |
| DIANTHUS THERAPEUTICS INC | COM | 252828108 | — | 400,000 shares | $38,992,000 |
| SUTRO BIOPHARMA INC | COM SHS | 869367201 | — | 1,172,487 shares | $38,926,568 |
| MODERNA INC | COM | 60770K107 | PUT | 500,000 shares | $35,015,000 |
| NUVALENT INC | COM | 670703107 | — | 275,000 shares | $33,962,500 |
| TREVI THERAPEUTICS INC | COM | 89532M101 | — | 1,800,172 shares | $33,573,208 |
| MODERNA INC | COM | 60770K107 | CALL | 475,000 shares | $33,264,250 |
| ARK ETF TR | GENOMIC REV ETF | 00214Q302 | CALL | 750,000 shares | $31,545,000 |
| OVID THERAPEUTICS INC | COM | 690469101 | — | 10,144,562 shares | $27,288,872 |
| LEXEO THERAPEUTICS INC | COM | 52886X107 | — | 5,807,611 shares | $27,034,429 |
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | — | 700,000 shares | $26,047,000 |
| BELITE BIO INC | SPONSORED ADS | 07782B104 | — | 165,000 shares | $25,407,525 |
| ENLIVEN THERAPEUTICS INC | COM | 29337E102 | — | 500,000 shares | $25,375,000 |
| FORTE BIOSCIENCES INC | COM NEW | 34962G208 | — | 1,145,391 shares | $24,339,559 |
| ELI LILLY & CO | COM | 532457108 | CALL | 20,000 shares | $23,988,600 |
| NURIX THERAPEUTICS INC | COM | 67080M103 | — | 967,620 shares | $23,474,461 |
| ALTO NEUROSCIENCE INC | COM SHS | 02157Q109 | — | 850,000 shares | $22,431,500 |
| MADRIGAL PHARMACEUTICALS INC | COM | 558868105 | — | 40,000 shares | $21,478,000 |
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | — | 172,125 shares | $21,099,083 |
| MINERALYS THERAPEUTICS INC | COM | 603170101 | — | 750,000 shares | $20,235,000 |
| RELAY THERAPEUTICS INC | COM | 75943R102 | — | 1,050,000 shares | $19,645,500 |
| SAGIMET BIOSCIENCES INC | COM SER A | 786700104 | — | 2,497,864 shares | $19,308,489 |
| JADE BIOSCIENCES INC | COM NEW | 008064206 | — | 840,350 shares | $18,672,577 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 | — | 450,000 shares | $17,415,000 |
| TRAVERE THERAPEUTICS INC | COM | 89422G107 | — | 300,000 shares | $17,043,000 |
| CULLINAN THERAPEUTICS INC | COM | 230031106 | — | 875,760 shares | $15,947,590 |
| SAVARA INC | COM | 805111101 | — | 2,512,153 shares | $15,474,862 |
| IDEAYA BIOSCIENCES INC | COM | 45166A102 | — | 400,000 shares | $14,908,000 |
| PERSPECTIVE THERAPEUTICS INC | COM NEW | 46489V302 | — | 4,214,582 shares | $14,371,725 |
| ODYSSEY THERAPEUTICS INC | COMMON STOCK | 67613T104 | — | 766,346 shares | $14,338,334 |
| COGENT BIOSCIENCES INC | NOTE 1.625%11/1 | 19240QAA0 | — | 11,000,000 principal | $13,653,740 |
| OMEROS CORP | COM | 682143102 | PUT | 1,411,300 shares | $13,421,463 |
| HELIX ACQUISITION CORP III | USD CL A ORD SHS | G4444S107 | — | 1,250,000 shares | $13,300,000 |
| EQUILLIUM INC | COM | 29446K106 | — | 4,100,000 shares | $13,120,000 |
| ALKERMES PLC | SHS | G01767105 | CALL | 250,000 shares | $13,098,750 |
| ESTABLISHMENT LABS HLDGS INC | COM | G31249108 | — | 148,013 shares | $12,700,996 |
| CLIMB BIO INC | COM | 28658R106 | — | 972,000 shares | $12,674,880 |
| TEVA PHARMACEUTICAL INDS LTD | SPONSORED ADS | 881624209 | — | 374,000 shares | $12,671,120 |
| VERADERMICS INC | COMMON STOCK | 922967104 | — | 100,000 shares | $12,294,000 |
| ARROWHEAD PHARMACEUTICALS IN | COM | 04280A100 | — | 150,000 shares | $12,226,500 |
| OMEROS CORP | NOTE 9.500% 6/1 | 682143AK8 | — | 6,525,000 principal | $12,182,372 |
| TAYSHA GENE THERAPIES INC | COM SHS | 877619106 | — | 1,750,000 shares | $11,917,500 |
| DAMORA THERAPEUTICS INC | COM NEW | 36322Q206 | — | 425,000 shares | $11,054,250 |
| EUPRAXIA PHARMACEUTICALS INC | COM | 29842P105 | — | 1,650,000 shares | $10,906,500 |
| VERA THERAPEUTICS INC | CL A | 92337R101 | — | 250,000 shares | $10,727,500 |
| PROQR THRAPEUTICS N V | SHS EURO | N71542109 | — | 5,543,936 shares | $10,311,721 |
| NEWAMSTERDAM PHARMA COMPANY | ORDINARY SHARES | N62509109 | — | 275,000 shares | $9,319,750 |
| KORRO BIO INC | COM | 500946108 | — | 706,904 shares | $9,316,995 |
| UNIQURE NV | SHS | N90064101 | CALL | 200,000 shares | $9,212,000 |
| ANTERIS TECHNOLOGIES GLOBAL | COM | 03675P102 | — | 912,397 shares | $8,987,110 |
| ZURA BIO LTD | CLASS A ORD SHS | G9TY5A101 | — | 1,464,303 shares | $8,639,388 |
| UNIQURE NV | SHS | N90064101 | — | 175,000 shares | $8,060,500 |
| ASCENDIS PHARMA A/S | ORD SHS | K08588103 | — | 30,000 shares | $8,001,600 |
| IBIO INC | COM NEW | 451033708 | — | 4,007,881 shares | $7,013,792 |
| GENERATE BIOMEDICINES INC | COM SHS | 370920100 | — | 400,000 shares | $6,748,000 |
| EVOMMUNE INC | COM SHS | 30054Y107 | PUT | 500,100 shares | $6,646,329 |
| TYRA BIOSCIENCES INC | COM | 90240B106 | — | 200,012 shares | $6,388,383 |
| SOL-GEL TECHNOLOGIES LTD | SHS NEW | M8694L137 | — | 84,900 shares | $6,294,486 |
| SAB BIOTHERAPEUTICS INC | COM NEW | 78397T202 | — | 1,525,000 shares | $5,947,500 |
| MACROGENICS INC | COM | 556099109 | — | 1,216,606 shares | $5,620,720 |
| CRISPR THERAPEUTICS AG | NAMEN AKT | H17182108 | — | 100,000 shares | $5,454,000 |
| NEWAMSTERDAM PHARMA COMPANY | *W EXP 99/99/999 | N62509117 | — | 245,000 shares | $5,343,450 |
| ASSEMBLY BIOSCIENCES INC | COM NEW | 045396207 | — | 190,000 shares | $5,221,200 |
| REZOLUTE INC | COM NEW | 76200L309 | — | 1,000,000 shares | $5,200,000 |
| PRECISION BIOSCIENCES INC | COM NEW | 74019P207 | — | 646,576 shares | $5,082,087 |
| HEMAB THERAPEUTICS HLDGS INC | COM SHS | 423494103 | — | 138,030 shares | $5,069,842 |
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 | — | 250,000 shares | $4,592,500 |
| ARRIVENT BIOPHARMA INC | COM | 04272N102 | — | 125,000 shares | $4,342,500 |
| VERRICA PHARMACEUTICALS INC | COM SHS | 92511W207 | — | 707,338 shares | $4,328,909 |
| COMPASS PATHWAYS PLC | SPONSORED ADS | 20451W101 | — | 301,183 shares | $4,261,739 |
| MBX BIOSCIENCES INC | COM | 55287L101 | — | 75,000 shares | $4,140,000 |
| RESEARCH ALLIANCE CORP III | ORD SHS CL A | G75226103 | — | 370,000 shares | $3,959,000 |
| IMMUNOVANT INC | COM | 45258J102 | — | 100,000 shares | $3,853,000 |
| AMANAT ACQUISITION CORP | CL A ORD | G0375M101 | — | 375,000 shares | $3,810,000 |
| BIOHAVEN LTD | COM | G1110E107 | — | 250,000 shares | $3,720,000 |
| FAETH THERAPEUTICS INC | COM NEW | 81728A207 | — | 144,404 shares | $3,610,100 |
| KARYOPHARM THERAPEUTICS INC | COM NEW | 48576U205 | — | 312,500 shares | $3,053,125 |
| ALECTOR INC | COM | 014442107 | — | 1,510,000 shares | $3,035,100 |
| SPYGLASS PHARMA INC | COM SHS | 85220G109 | — | 131,586 shares | $2,929,104 |
| CRINETICS PHARMACEUTICALS IN | COM | 22663K107 | — | 75,000 shares | $2,806,500 |
| OAKTREE ACQUISITION CORP III | UNIT 10/04/2029 | G6717R120 | — | 250,000 shares | $2,750,000 |
| CELCUITY INC | NOTE 0.250% 8/0 | 15102KAB6 | — | 2,000,000 principal | $2,282,800 |
| JATT II ACQUISITION CORP | ORD SHS | G50765109 | — | 200,000 shares | $2,272,000 |
| NEUMORA THERAPEUTICS INC. | COM | 640979100 | — | 1,070,651 shares | $1,820,107 |
| AMYLYX PHARMACEUTICALS INC | COM | 03237H101 | — | 98,999 shares | $1,778,022 |
| ADLAI NORTYE LTD | SPONSORED ADS | 00704R109 | — | 153,847 shares | $1,769,241 |