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Avoro Capital Advisors LLC
Period ended Jun 30, 2026 · Latest filing Aug 14, 2026
These quarterly holdings are delayed and may not include all assets or short positions.
Values are from the reporting date, not current prices or purchase costs.
The same security may appear in multiple rows.
Source: SEC
Reported portfolio value
Quarter-end reported holdings; not current value or investment performance.
View reported values
- Jun 30, 2026: $11,136,250,185
More quarters will appear as history becomes available.
Top holdings
Top 10 at Jun 30, 2026. Matching entries are combined; security classes and options remain separate. Shares exclude principal amounts; option shares reflect the reported underlying amount.
View top holdings values
- UNITED THERAPEUTICS CORP · Common · 91307C102 · shares: $1,505,082,912
- ASCENDIS PHARMA · ORDINARY SHARES · K08588103 · shares: $1,363,235,526
- KRYSTAL BIOTECH INC · Common · 501147102 · shares: $1,073,713,003
- MADRIGAL PHARMACEUTICALS INC · Common · 558868105 · shares: $984,408,154
- ARGENX SE · Sponsored ADR · 04016X101 · shares: $927,770,000
- ARROWHEAD PHARMACEUTICALS INC · Common · 04280A100 · shares: $925,591,288
- KYMERA THERAPEUTICS INC · Common · 501575104 · shares: $857,129,238
- REVOLUTION MEDICINES INC · Common · 76155X100 · shares: $430,182,160
- CYTOKINETICS INC · Common · 23282W605 · shares: $425,949,915
- CELCUITY INC · Common · 15102K100 · shares: $355,708,000
Reported holdings
26 reported entries| Issuer | Class | CUSIP | Type | Shares / principal | Reported value (USD) |
|---|---|---|---|---|---|
| UNITED THERAPEUTICS CORP | Common | 91307C102 | — | 2,777,777 shares | $1,505,082,912 |
| ASCENDIS PHARMA | ORDINARY SHARES | K08588103 | — | 5,111,111 shares | $1,363,235,526 |
| KRYSTAL BIOTECH INC | Common | 501147102 | — | 2,888,888 shares | $1,073,713,003 |
| MADRIGAL PHARMACEUTICALS INC | Common | 558868105 | — | 1,833,333 shares | $984,408,154 |
| ARGENX SE | Sponsored ADR | 04016X101 | — | 1,000,000 shares | $927,770,000 |
| ARROWHEAD PHARMACEUTICALS INC | Common | 04280A100 | — | 11,355,555 shares | $925,591,288 |
| KYMERA THERAPEUTICS INC | Common | 501575104 | — | 7,474,747 shares | $857,129,238 |
| REVOLUTION MEDICINES INC | Common | 76155X100 | — | 2,297,000 shares | $430,182,160 |
| CYTOKINETICS INC | Common | 23282W605 | — | 4,999,999 shares | $425,949,915 |
| CELCUITY INC | Common | 15102K100 | — | 3,400,000 shares | $355,708,000 |
| STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 | — | 6,555,555 shares | $351,836,637 |
| XENON PHARMACEUTICALS INC | Common | 98420N105 | — | 5,777,777 shares | $348,746,620 |
| DEFINIUM THERAPEUTICS INC | Common | 24477V105 | — | 7,188,888 shares | $338,165,292 |
| UNIQURE NV | Common | N90064101 | — | 6,727,777 shares | $309,881,409 |
| VERA THERAPEUTICS INC | Common | 92337R101 | — | 5,723,888 shares | $245,612,034 |
| TAYSHA GENE THERAPIES INC | Common | 877619106 | — | 23,888,888 shares | $162,683,327 |
| OCULAR THERAPEUTIX INC | Common | 67576A100 | — | 12,540,000 shares | $123,142,800 |
| DAMORA THERAPEUTICS INC | Common | 36322Q206 | — | 3,783,000 shares | $98,395,830 |
| HEMAB THERAPEUTICS HLDGS INC | Common | 423494103 | — | 1,925,150 shares | $70,710,760 |
| GH RESEARCH PLC | ORDINARY SHARES | G3855L106 | — | 1,800,000 shares | $48,384,000 |
| VIRIDIAN THERAPEUTICS INC | Common | 92790C104 | — | 2,500,000 shares | $45,925,000 |
| SEPTERNA INC | Common | 81734D104 | — | 1,337,500 shares | $44,792,875 |
| AVALO THERAPEUTICS | Common | 05338F306 | — | 2,333,333 shares | $43,119,994 |
| FAETH THERAPEUTICS INC | COMMON | 81728A207 | — | 1,444,039 shares | $36,100,975 |
| WHITEHAWK THERAPEUTICS INC | Common | 00032Q104 | — | 2,849,402 shares | $13,050,261 |
| LEXEO THERAPEUTICS INC | Common | 52886X107 | — | 1,489,189 shares | $6,932,175 |