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COMMODORE CAPITAL LP
Period ended Jun 30, 2026 · Latest filing Aug 14, 2026
These quarterly holdings are delayed and may not include all assets or short positions.
Values are from the reporting date, not current prices or purchase costs.
The same security may appear in multiple rows.
Source: SEC
Reported portfolio value
Quarter-end reported holdings; not current value or investment performance.
View reported values
- Jun 30, 2026: $1,678,964,770
More quarters will appear as history becomes available.
Top holdings
Top 10 at Jun 30, 2026. Matching entries are combined; security classes and options remain separate. Shares exclude principal amounts; option shares reflect the reported underlying amount.
View top holdings values
- RELAY THERAPEUTICS INC · COM · 75943R102 · shares: $224,520,000
- ENLIVEN THERAPEUTICS INC · COM · 29337E102 · shares: $166,206,250
- ALKERMES PLC · SHS · G01767105 · shares: $157,185,000
- COGENT BIOSCIENCES INC · COM · 19240Q201 · shares: $118,035,000
- AMYLYX PHARMACEUTICALS INC · COM · 03237H101 · shares: $101,474,000
- DEFINIUM THERAPEUTICS INC · COM SHS · 24477V105 · shares: $94,080,000
- SPYRE THERAPEUTICS INC · COM NEW · 00773J202 · shares: $75,177,661
- ALTO NEUROSCIENCE INC · COM SHS · 02157Q109 · shares: $71,865,142
- TANGO THERAPEUTICS INC · COM · 87583X109 · shares: $70,335,000
- EYEPOINT INC · COM NEW · 30233G209 · shares: $65,780,000
Reported holdings
33 reported entries| Issuer | Class | CUSIP | Type | Shares / principal | Reported value (USD) |
|---|---|---|---|---|---|
| RELAY THERAPEUTICS INC | COM | 75943R102 | — | 12,000,000 shares | $224,520,000 |
| ENLIVEN THERAPEUTICS INC | COM | 29337E102 | — | 3,275,000 shares | $166,206,250 |
| ALKERMES PLC | SHS | G01767105 | — | 3,000,000 shares | $157,185,000 |
| COGENT BIOSCIENCES INC | COM | 19240Q201 | — | 3,050,000 shares | $118,035,000 |
| AMYLYX PHARMACEUTICALS INC | COM | 03237H101 | — | 5,650,000 shares | $101,474,000 |
| DEFINIUM THERAPEUTICS INC | COM SHS | 24477V105 | — | 2,000,000 shares | $94,080,000 |
| SPYRE THERAPEUTICS INC | COM NEW | 00773J202 | — | 846,786 shares | $75,177,661 |
| ALTO NEUROSCIENCE INC | COM SHS | 02157Q109 | — | 2,723,196 shares | $71,865,142 |
| TANGO THERAPEUTICS INC | COM | 87583X109 | — | 2,250,000 shares | $70,335,000 |
| EYEPOINT INC | COM NEW | 30233G209 | — | 4,600,000 shares | $65,780,000 |
| TYRA BIOSCIENCES INC | COM | 90240B106 | — | 1,875,000 shares | $59,887,500 |
| DAMORA THERAPEUTICS INC | COM NEW | 36322Q206 | — | 1,939,000 shares | $50,433,390 |
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | — | 1,350,000 shares | $50,233,500 |
| PHARVARIS N V | COM | N69605108 | — | 1,425,000 shares | $49,276,500 |
| LB PHARMACEUTICALS INC | COM SHS | 50180M108 | — | 1,500,000 shares | $48,682,500 |
| ASSEMBLY BIOSCIENCES INC | COM NEW | 045396207 | — | 1,415,000 shares | $38,884,200 |
| EDITAS MEDICINE INC | COM | 28106W103 | — | 8,889,000 shares | $28,800,360 |
| KYMERA THERAPEUTICS INC | COM | 501575104 | — | 250,000 shares | $28,667,500 |
| PERSPECTIVE THERAPEUTICS INC | COM NEW | 46489V302 | — | 6,336,782 shares | $21,608,427 |
| CENTURY THERAPEUTICS INC | COM | 15673T100 | — | 8,695,652 shares | $21,304,347 |
| ZURA BIO LTD | CLASS A ORD SHS | G9TY5A101 | — | 3,250,000 shares | $19,175,000 |
| AVALO THERAPEUTICS INC | COM NEW | 05338F306 | — | 1,018,319 shares | $18,818,535 |
| INFLARX NV | COM | N44821101 | — | 7,300,000 shares | $16,352,000 |
| AN2 THERAPEUTICS INC | COM | 037326105 | — | 2,933,680 shares | $14,199,011 |
| NUVALENT INC | COM | 670703107 | — | 100,000 shares | $12,350,000 |
| SAB BIOTHERAPEUTICS INC | COM NEW | 78397T202 | — | 2,870,000 shares | $11,193,000 |
| INHIBIKASE THERAPEUTICS INC | COM NEW | 45719W205 | — | 5,397,488 shares | $10,956,901 |
| RELMADA THERAPEUTICS INC | COM | 75955J402 | — | 1,425,000 shares | $9,861,000 |
| PEPGEN INC | COM | 713317105 | — | 4,475,000 shares | $8,055,000 |
| RESEARCH ALLIANCE CORP III | ORD SHS CL A | G75226103 | — | 500,000 shares | $5,350,000 |
| HELIX ACQUISITION CORP III | USD CL A ORD SHS | G4444S107 | — | 500,000 shares | $5,320,000 |
| LEONABIO INC | COM | 04746L203 | — | 464,398 shares | $4,267,818 |
| VISTAGEN THERAPEUTICS INC | COM | 92840H400 | — | 2,788,620 shares | $630,228 |