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Soleus Capital Management, L.P.
Period ended Jun 30, 2026 · Latest filing Aug 11, 2026
These quarterly holdings are delayed and may not include all assets or short positions.
Values are from the reporting date, not current prices or purchase costs.
The same security may appear in multiple rows.
Source: SEC
Reported portfolio value
Quarter-end reported holdings; not current value or investment performance.
View reported values
- Jun 30, 2026: $2,901,979,696
More quarters will appear as history becomes available.
Top holdings
Top 10 at Jun 30, 2026. Matching entries are combined; security classes and options remain separate. Shares exclude principal amounts; option shares reflect the reported underlying amount.
View top holdings values
- KRYSTAL BIOTECH INC · COM · 501147102 · shares: $349,092,534
- CELCUITY INC · COM · 15102K100 · shares: $178,305,749
- TG THERAPEUTICS INC · COM · 88322Q108 · shares: $160,858,551
- INSULET CORP · COM · 45784P101 · shares: $159,710,250
- NOVOCURE LTD · ORD SHS · G6674U108 · shares: $150,188,025
- UNITED THERAPEUTICS CORP DEL · COM · 91307C102 · shares: $122,229,804
- INSPIRE MED SYS INC · COM · 457730109 · shares: $86,161,360
- RIGEL PHARMACEUTICALS INC · COM · 766559702 · shares: $72,117,876
- ANI PHARMACEUTICALS INC · COM · 00182C103 · shares: $71,833,173
- BETA BIONICS INC · COM · 08659B102 · shares: $68,849,498
Reported holdings
97 reported entries| Issuer | Class | CUSIP | Type | Shares / principal | Reported value (USD) |
|---|---|---|---|---|---|
| KRYSTAL BIOTECH INC | COM | 501147102 | — | 939,254 shares | $349,092,534 |
| CELCUITY INC | COM | 15102K100 | — | 1,704,318 shares | $178,305,749 |
| TG THERAPEUTICS INC | COM | 88322Q108 | — | 2,927,895 shares | $160,858,551 |
| INSULET CORP | COM | 45784P101 | — | 1,049,000 shares | $159,710,250 |
| NOVOCURE LTD | ORD SHS | G6674U108 | — | 9,913,401 shares | $150,188,025 |
| UNITED THERAPEUTICS CORP DEL | COM | 91307C102 | — | 225,587 shares | $122,229,804 |
| INSPIRE MED SYS INC | COM | 457730109 | — | 1,931,436 shares | $86,161,360 |
| RIGEL PHARMACEUTICALS INC | COM | 766559702 | — | 1,843,504 shares | $72,117,876 |
| ANI PHARMACEUTICALS INC | COM | 00182C103 | — | 867,760 shares | $71,833,173 |
| BETA BIONICS INC | COM | 08659B102 | — | 4,393,714 shares | $68,849,498 |
| VERICEL CORP | COM | 92346J108 | — | 1,459,152 shares | $64,917,672 |
| PRAXIS PRECISION MEDICINES I | COM NEW | 74006W207 | — | 177,517 shares | $59,430,916 |
| GERON CORP | COM | 374163103 | — | 42,808,659 shares | $54,795,084 |
| ALKERMES PLC | SHS | G01767105 | — | 1,029,252 shares | $53,927,659 |
| ERASCA INC | COM | 29479A108 | — | 2,700,000 shares | $49,464,000 |
| NEUROPACE INC | COM | 641288105 | — | 2,911,122 shares | $46,257,729 |
| PROGYNY INC | COM | 74340E103 | — | 1,602,000 shares | $46,185,660 |
| INDIVIOR PHARMACEUTICALS INC | COM | 45579U109 | — | 1,064,000 shares | $43,655,920 |
| PARABILIS MEDICINES INC | COM | 698955101 | — | 1,465,070 shares | $40,098,966 |
| EDAP TMS S A | SPONSORED ADR | 268311107 | — | 7,309,254 shares | $37,861,936 |
| GLOBUS MED INC | CL A | 379577208 | — | 468,922 shares | $37,049,527 |
| ARCUS BIOSCIENCES INC | COM | 03969F109 | — | 1,168,738 shares | $36,032,193 |
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | — | 1,628,039 shares | $35,588,933 |
| NURIX THERAPEUTICS INC | COM | 67080M103 | — | 1,465,163 shares | $35,544,854 |
| LEGEND BIOTECH CORP | SPONSORED ADS | 52490G102 | — | 1,205,000 shares | $34,800,400 |
| JADE BIOSCIENCES INC | COM NEW | 008064206 | — | 1,550,690 shares | $34,456,332 |
| UNITEDHEALTH GROUP INC | COM | 91324P102 | — | 80,000 shares | $33,250,400 |
| AVALO THERAPEUTICS INC | COM NEW | 05338F306 | — | 1,654,978 shares | $30,583,993 |
| UROGEN PHARMA LTD | COM | M96088105 | — | 829,810 shares | $30,537,008 |
| MBX BIOSCIENCES INC | COM | 55287L101 | — | 515,279 shares | $28,443,401 |
| PALISADE BIO INC | COM | 696389402 | — | 13,063,687 shares | $27,303,106 |
| PHARVARIS N V | COM | N69605108 | — | 730,907 shares | $25,274,764 |
| ORGANOGENESIS HLDGS INC | COM | 68621F102 | — | 10,140,951 shares | $24,642,511 |
| SUPERNUS PHARMACEUTICALS | COM | 868459108 | — | 520,000 shares | $24,185,200 |
| PROCEPT BIOROBOTICS CORP | COM | 74276L105 | — | 1,003,000 shares | $22,647,740 |
| TANGO THERAPEUTICS INC | COM | 87583X109 | — | 709,000 shares | $22,163,340 |
| INHIBIKASE THERAPEUTICS INC | COM NEW | 45719W205 | — | 10,875,000 shares | $22,076,250 |
| TREVI THERAPEUTICS INC | COM | 89532M101 | — | 1,179,618 shares | $21,999,876 |
| BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 | — | 375,572 shares | $21,490,230 |
| LIVANOVA PLC | SHS | G5509L101 | — | 254,957 shares | $20,965,114 |
| ARGENX SE | SPONSORED ADR | 04016X101 | — | 19,955 shares | $18,513,650 |
| NUVECTIS PHARMA INC | COM | 67080T108 | — | 1,000,000 shares | $18,390,000 |
| CAPRICOR THERAPEUTICS INC | COM NEW | 14070B309 | — | 761,737 shares | $18,342,627 |
| EDGEWISE THERAPEUTICS INC | COM | 28036F105 | — | 450,889 shares | $18,319,620 |
| PRELUDE THERAPEUTICS INC | COM | 74065P101 | — | 3,378,378 shares | $18,006,755 |
| XENON PHARMACEUTICALS INC | COM | 98420N105 | — | 267,000 shares | $16,116,120 |
| C4 THERAPEUTICS INC | COM STK | 12529R107 | — | 3,377,981 shares | $15,775,171 |
| KINIKSA PHARMACEUTICALS INTL | ORD SHS CL A | G52694109 | — | 246,353 shares | $15,754,274 |
| ORTHOPEDIATRICS CORP | COM | 68752L100 | — | 732,144 shares | $14,005,915 |
| AVALYN PHARMACEUTICALS INC | COM SHS | 05348Y105 | — | 419,000 shares | $13,793,480 |
| BIODESIX INC | COM | 09075X207 | — | 585,958 shares | $13,213,353 |
| SPYRE THERAPEUTICS INC | COM NEW | 00773J202 | — | 147,000 shares | $13,050,660 |
| TWIST BIOSCIENCE CORP | COM | 90184D100 | — | 104,629 shares | $10,764,232 |
| VIR BIOTECHNOLOGY INC | COM | 92764N102 | — | 1,000,000 shares | $10,190,000 |
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | — | 33,050 shares | $9,949,042 |
| IMMUNOVANT INC | COM | 45258J102 | — | 252,000 shares | $9,709,560 |
| INSMED INC | COM PAR $.01 | 457669307 | — | 90,250 shares | $9,622,455 |
| SEPTERNA INC | COM | 81734D104 | — | 275,000 shares | $9,209,750 |
| SOPHIA GENETICS SA | ORDINARY SHARES | H82027105 | — | 1,565,000 shares | $9,030,050 |
| NEKTAR THERAPEUTICS | COM NEW | 640268306 | — | 128,362 shares | $8,960,951 |
| MIRUM PHARMACEUTICALS INC | COM | 604749101 | — | 75,000 shares | $8,780,250 |
| ARTIVION INC | COM | 228903100 | — | 388,000 shares | $8,718,360 |
| TANDEM DIABETES CARE INC | COM NEW | 875372203 | — | 575,000 shares | $8,676,750 |
| ENLIVEN THERAPEUTICS INC | COM | 29337E102 | — | 165,677 shares | $8,408,108 |
| SIONNA THERAPEUTICS INC | COM | 829401108 | — | 177,687 shares | $7,816,451 |
| BELITE BIO INC | SPONSORED ADS | 07782B104 | — | 50,524 shares | $7,779,938 |
| CERUS CORP | COM | 157085101 | — | 2,500,000 shares | $7,300,000 |
| SILENCE THERAPEUTICS PLC | ADS | 82686Q101 | — | 630,000 shares | $6,917,400 |
| IMMUNIC INC | COM NEW | 4525EP200 | — | 450,000 shares | $6,916,500 |
| INVIVYD INC | COM | 00534A102 | — | 7,708,727 shares | $6,725,093 |
| MERCK & CO INC | COM | 58933Y105 | — | 50,000 shares | $6,425,000 |
| RELMADA THERAPEUTICS INC | COM | 75955J402 | — | 842,106 shares | $5,827,374 |
| STRUCTURE THERAPEUTICS INC | SPONSORED ADS | 86366E106 | — | 107,000 shares | $5,742,690 |
| EVOLUS INC | COM | 30052C107 | — | 822,428 shares | $5,707,650 |
| ADLAI NORTYE LTD | SPONSORED ADS | 00704R109 | — | 405,523 shares | $4,663,515 |
| ZENTALIS PHARMACEUTICALS INC | COM | 98943L107 | — | 950,000 shares | $4,607,500 |
| KARYOPHARM THERAPEUTICS INC | COM NEW | 48576U205 | — | 440,000 shares | $4,298,800 |
| CONTEXT THERAPEUTICS INC | COM | 21077P108 | — | 7,063,141 shares | $3,912,274 |
| PULMONX CORP | COM | 745848101 | — | 2,788,323 shares | $3,624,820 |
| SAB BIOTHERAPEUTICS INC | COM NEW | 78397T202 | — | 900,000 shares | $3,510,000 |
| TECTONIC THERAPEUTIC INC | COM | 878972108 | — | 101,684 shares | $3,495,388 |
| AXOGEN INC | COM | 05463X106 | — | 57,036 shares | $2,634,493 |
| SATELLOS BIOSCIENCE INC | COM | 80401L803 | — | 314,359 shares | $2,444,141 |
| ARRIVENT BIOPHARMA INC | COM | 04272N102 | — | 50,000 shares | $1,737,000 |
| CORCEPT THERAPEUTICS INC | COM | 218352102 | — | 19,653 shares | $1,708,828 |
| SOLID BIOSCIENCES INC | COM NEW | 83422E204 | — | 150,000 shares | $1,498,500 |
| VERACYTE INC | COM | 92337F107 | — | 25,000 shares | $1,468,250 |
| CULLINAN THERAPEUTICS INC | COM | 230031106 | — | 50,000 shares | $910,500 |
| INSPIREMD INC | COM | 45779A846 | — | 1,045,708 shares | $732,100 |
| GENEDX HOLDINGS CORP | COM CL A | 81663L200 | — | 10,000 shares | $686,500 |
| IOVANCE BIOTHERAPEUTICS INC | COM | 462260100 | — | 150,000 shares | $624,000 |
| LARIMAR THERAPEUTICS INC | COM | 517125100 | — | 188,102 shares | $573,711 |
| CG ONCOLOGY INC | COM | 156944100 | — | 5,000 shares | $355,250 |
| QUOIN PHARMACEUTICALS LTD | SPONSORED ADS | 74907L409 | — | 72,730 shares | $352,013 |
| EQUILLIUM INC | COM | 29446K106 | — | 90,000 shares | $288,000 |
| NATERA INC | COM | 632307104 | — | 1,000 shares | $271,450 |
| NEOGENOMICS INC | COM NEW | 64049M209 | — | 10,000 shares | $145,900 |